REGULATED LIFE SCIENCES

Decisions you can defend.

AI is fast but can't prove its work. In regulated life sciences, that's disqualifying. CoReason constrains AI as it works, so every output follows the standards your field already trusts and every step is recorded as it happens. Evidence you can hand to a regulator, an auditor, or a payer.

The Problem
Sooner or later, someone asks how you got the number.
A regulator. An auditor. A payer. Too often the honest answer is a spreadsheet someone left behind, a definition that quietly shifted, an explanation written after the fact. The scale of what's at stake:
over70%
of researchers surveyed have tried and failed to reproduce another scientist's experiments
source: Nature survey of 1,576 researchers · Baker, M. Nature 533, 452–454 (2016)
8.3% 16.6%
obesity prevalence in the same 1,026 children, depending only on which growth reference defines it
source: Twells & Newhook, BMC Pediatrics (2011) · CDC vs. IOTF reference
73
FDA medical-device authorizations that drew on real-world evidence in five years (FY2020–2025), decisions that have to hold up
One Platform Underneath
The workflows differ. What makes them defensible doesn't.
Each stage below is a different application of the same proprietary platform. The grounding in your field's standards, the record written as the work happens, the re-run that has to match — these are properties of the platform, not features rebuilt for each workflow. Built on industry-standard agent frameworks. Deployed in your environment. A new workflow inherits its defensibility on day one.
Evidence Planning
Trial Design
Regulatory Submission
Market Access
Pharmacovigilance
Real-World Evidence
The CoReason Platform — What Every Workflow Inherits

Grounding

Where a standard exists, the model doesn't get a vote. A code is retrieved from MedDRA, RxNorm, SNOMED, OMOP — or it does not appear.

The record

Written as the work happens, not reconstructed after. What an auditor reads is the actual path, including where a human intervened.

Re-runs

Every output versioned and re-runnable. Run it again in a year: same answer. A divergence is a finding we surface, not a surprise you meet in an inspection.

Sign-off

Judgment calls are held for a named human, with the evidence assembled. Nothing ships unsigned.

Built on industry-standard agent frameworks · Deployed in your environment, so your data stays in your cloud

One asset, end to end

Watch it work.

Six stages of an asset's life, one shape of work: something unstructured goes in, every step is grounded in the method your field already trusts, and every run ends the same way: someone else re-runs it, and it matches.

Select a stage of the asset's life
illustrative run — synthetic data

queued

1Input
The narrative, and the standard it answers to
2The work
Each step, recorded as it is taken: the record an auditor reads
3Output
The deliverable, and where it came from

WHY WE ARE DIFFERENT

AI shouldn’t guess where a standard already exists.

A general-purpose model doesn’t reason badly. It reasons where your field already settled the question, and can’t tell you how it got there. Three things follow.

Where a standard exists, the model doesn’t get a vote.

Your field spent decades building what a model is tempted to improvise: vocabularies, causality frameworks, pricing formulas, registries. A code is retrieved or it does not appear. A number is computed or it is not reported. Reasoning happens around those fixed points, never through them.

USE THE METHOD, DON’T APPROXIMATE IT

01

The record is written as the work happens.

An explanation written after the fact is a story about a decision. Each step is captured as it is taken, including where a human intervened, and why. What an auditor reads is the actual path. Where a claim has no source, the record says so.

THE TRAIL IS THE ARTIFACT

02

Run it again in a year. Same answer.

Reproducibility is the basis of defending a result to someone who wasn't in the room. Outputs are versioned and re-runnable. A re-run that diverges is a finding we surface, not a surprise you meet in an inspection.

THE TRAIL IS THE ARTIFACT

03

Underneath all three: everything we produce is reproducible and defensible to a third party. Data you can trace. Cohorts anyone can re-run. Packages a reviewer can sign. Same verb, different object. That is the whole company.

WORKING WITH US

Start small. Keep what we find.

We don’t ask you to commit to a program before either side has evidence. Every engagement follows the same path.

It starts with a working session. Thirty minutes, no deck. Bring the actual problem: the codelist nobody trusts, the cohort that won’t reproduce. We walk through it and show you the trail it leaves.

Then a two-week discovery sprint. Fixed fee, credited in full against the first delivery engagement awarded within ninety days. Week one, working sessions with your data and clinical teams: we map what you have, what you’re being asked to produce, and where the two don’t meet. Week two, we build one narrow worked example end to end on your own material and write it up.

You keep the output either way. A written assessment of your current estate, a worked example you can show internally, and a costed plan with a named team and a delivery date. If the assessment is useful and the plan is credible, that’s the basis for a larger conversation. If not, your exposure was two weeks.

TEAM

We've been the ones checking.

The data standards 300+ institutions run on. A launch carried to $6.5B. FDA breakthrough designations. This team has spent its careers on the reviewing side of evidence.

Gowtham Rao, MD, PhD

CEO / FOUNDER

Board Certified Physician licensed in NY, PA, WI, SC. PhD in Epidemiology and Biostatistics. Led development of observational health data systems adopted by 300+ institutions globally through OHDSI. Senior Director at Johnson & Johnson. Life Sciences Consultant at EPAM Systems. Former Chief Medical Informatics Officer at BlueCross BlueShield. VA Research Physician. 15+ years building the infrastructure for how the pharmaceutical industry generates and evaluates clinical evidence. The reasoning frameworks and data models in CoReason are deeply informed by that work.

Troy Sarich, PhD

Senior Strategic Advisor

20+ years at Johnson & Johnson. Former SVP & Chief Commercial Data Science Officer. Led XARELTO® from development through $6.5B in global sales. Co-founded the J&J AI Council.

Trilok Parekh, PhD

Senior Strategic Advisor

25+ years at J&J. Oncology CDT Lead. FDA Breakthrough Therapy Designations. Biomarkers & Real-World Evidence.

Amit Parikh, Esq

Strategic Advisor

IP & Technology. AI governance, patent strategy, equity structuring.

Asha Mahesh

Data Officer

Former JNJ Exec, Data Platforms & Privacy. Enterprise data architecture, governance, and compliance.

Ammar Shallal

Founding Investor

Operator and early-stage investor. 5+ ventures built across technology and services.

David Youmans, MD

Clinical Advisor

Healthcare executive with 25+ years of leadership in the clinical research organization (CRO) industry. Former Chair of Radiology at Penn Medicine Princeton Health, bringing combined expertise across clinical trials and health system operations.

WHERE OUR TEAM HAS WORKED

Johnson & Johnson · Roche · OHDSI · Bristol Myers Squibb · Penn Medicine · Accenture · BlueCross BlueShield